Ampicillin是一种广谱、半合成的β-内酰胺类青霉素抗生素,具有杀菌活性。
产品描述
Ampicillin is a broad-spectrum, semi-synthetic, beta-lactam penicillin antibiotic with bactericidal activity.
体外活性
Ampicillin inhibits the growth of E. coli of swine origin in a dose-dependent way. The effective inhibitory concentration of Ampicillin was 2.5 uG/mL[1].
体内活性
Ampicillin is extremely effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig[1]. Ampicillin produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood[2]. Ampicillin provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with ampicillin significantly reduces medial hippocampal cell death following global forebrain ischemia[3].
Cas No.
69-53-4
分子式
C16H19N3O4S
分子量
349.41
别名
D-(-)-α-Aminobenzylpenicillin;氨苄青霉素;Amcill;Aminobenzylpenicillin;Ampicillin acid
储存和溶解度
DMSO:>10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years