Prosaikogenin F是一种单糖苷,具有溶血和抗癌特性。
产品描述
Prosaikogenin F is a natural product with anticancer and hemolytic properties [1].
体外活性
Prosaikogenin F suppressed A549 proliferation with inhibition rates of 40.53%, 92.62% and 93.07% at concentrations of 20, 40 and 60 μg/mL, respectively [1]. The IC50 values of prosaikogenin F on HCT 116 cancer cells was 14.21 μM [2].
体内活性
Intraperitoneal administration of Saikosaponin A and its intestinal metabolite, Prosaikogenin F, showed corticosterone secretion-inducing activity at a dose of 0.1 mmol/kg, and maximally increase it at a dose of 0.4 mmol/kg [3].
Cas No.
99365-20-5
分子式
C36H58O8
分子量
618.84
别名
(2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3,4,5-triol;前柴胡皂苷F
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years