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Prosaikogenin F
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Prosaikogenin F图片
CAS NO:99365-20-5
包装与价格:
包装价格(元)
5 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
(2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3,4,5-triol
前柴胡皂苷F
产品介绍
Prosaikogenin F是一种单糖苷,具有溶血和抗癌特性。

产品描述

Prosaikogenin F is a natural product with anticancer and hemolytic properties [1].

体外活性

Prosaikogenin F suppressed A549 proliferation with inhibition rates of 40.53%, 92.62% and 93.07% at concentrations of 20, 40 and 60 μg/mL, respectively [1]. The IC50 values of prosaikogenin F on HCT 116 cancer cells was 14.21 μM [2].

体内活性

Intraperitoneal administration of Saikosaponin A and its intestinal metabolite, Prosaikogenin F, showed corticosterone secretion-inducing activity at a dose of 0.1 mmol/kg, and maximally increase it at a dose of 0.4 mmol/kg [3].

Cas No.

99365-20-5

分子式

C36H58O8

分子量

618.84

别名

(2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3,4,5-triol;前柴胡皂苷F

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years