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Ansatrienin A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ansatrienin A图片
CAS NO:82189-03-5
包装:5 mg
市场价:7874元

产品介绍

产品描述

Ansatrienin A is an ansamycin antibiotic and antifungal agent first isolated from S. collinus and S. rishiriensis. In fetal rat long bones, it is an inhibitor of parathyroid hormone-induced calcium release (IC50 = 64 nM), which is a measure of bone resorption, and pp60c-srcM kinase (IC50 = 100 nM). It also inhibits TNF-α-induced expression of intercellular adhesion molecule-1 (ICAM-1; IC50 = 570 nM). Early in vitro studies showed that ansatrienin A potentiates the chemotherapeutic action of 5-fluorouracil , cisplatin , bleomycin , mitomycin C , and 6-mercaptopurine. It is an oxidized form of ansatrienin B .

Cas No.

82189-03-5

分子式

C36H48N2O8

分子量

636.786

储存和溶解度

Methanol:Soluble
DMF:Soluble
Ethanol:Soluble
DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years