Lucigenin 是化学发光探针,可用于检测内源性产生的超氧阴离子自由基在细胞的存在。
产品描述
Lucigenin (L-6868) is a chemiluminescent probe used to indicate the presence of endogenously generated superoxide anion radicals in cells.
体外活性
Upon single-electron reduction of Lucigenin by a radical species the subsequent form of Lucigenin presents amplified chemiluminescence which is measurable and can be correlated to the respective amount of reactive radical species present in the system. In addition to indicating the presence of radicals in cells, Lucigenin shows interaction with redox-active oxidoreductase enzymes. Lucigenin is shown to mediate the reduction of cytochrome C by xanthine oxidase and to increase the rate of NADPH oxidation.
Cas No.
2315-97-1
分子式
C28H22N3O3
分子量
448.49
别名
NSC-151912;L-6868;光泽精
储存和溶解度
DMSO:80mg/mL (156.71 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years