EZH2-IN-5 is a potent EZH2 inhibitor with IC 50 values of 1.52 nM and 4.07 nM for wild-type and mutant Tyr641 EZH2, respectively.

EZH2-IN-5 (compound 276) inhibits cell growth of WSUDLCL2 cell lines with an IC 50 of 187.28 nM[1].

1403258-69-4

C26H37BrN4O2

517.5

EZH2-IN-5

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years