GLP-1(32-36)amide acetate是一种五肽，衍生自糖调节激素 GLP-1 的 C 末端。GLP-1(32-36)amide acetate可抑制糖尿病小鼠的体重增加并调节全身葡萄糖代谢。

GLP-1(32-36)amide acetate is a pentapeptide and derived from the C terminus of the glucoregulatory hormone GLP-1. GLP-1(32-36)amide acetate could inhibit weight gain and modulate whole body glucose metabolism in diabetic mice.

GLP-1(32-36)amide acetate (0.1-10 μM; 24 h) retains cell viability and decreases apoptosis against Streptozotocin (STZ; 1 μM) in INS‐1 cells[1].

GLP-1(32-36)amide acetate(1 μmol/kg; i.p. once daily for 21 d) protects islet from damage, inhibits weight gain, and relieves symptoms of polydipsia in diabetic mice[1].GLP-1(32-36)amide acetate(1 μmol/kg; a single i.p.) slightly reduces the mean glucose lever at 30 min after the challenge of glucose in normal mice[1]. GLP-1(32-36)amide acetate(50-70 nmol/kg/d; infusion for 12-16 weeks) prevents the development of diet-induced obesity and hepatic steatosis in high fat-fed mice[2].

C27H54N10O7

630.78

GLP-1(32-36)amide 醋酸盐;GLP-1(32-36)amide acetate(1417302-71-6 Free base)

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years