Solutol HS-15 是一种通透性增强剂，是一种 Macrogol 15 羟基硬脂酸酯。

Solutol HS-15 is a permeability enhancer.

Solutol HS-15 promotes the apical-to-basolateral translocation of a model protein (insulin) across Calu-3 monolayers when applied at 37°C. Furthermore there is no statistically significant increase in insulin permeability in the presence of Solutol HS-15, relative to the respective control, at 4°C. Solutol HS-15 treated cells show a statistically significant increase in permeability towards lower molecular weight permeants (5 to 22 kDa) and an absence of a statistically significant increase in permeability of proteins with larger molecular weight, namely albumin and IgG (P>0.05 relative to control).

61909-81-7

C20H40O4

344.53

Solutol HS-15

Ethanol:100 mg/mL,Need ultrasonic
H2O:25 mg/mL,Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years