2-Di-1-ASP 是单苯乙烯基染料,对 G-四链体和双链 DNA 具有选择性。它普遍用作双链 DNA 的线粒体染色和凹槽结合荧光探针。
产品描述
2-Di-1-ASP is a mono-stryryl dye and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. It has selective for G-quadruplex (G4) and double-stranded DNA.
体外活性
2-Di-1-ASP (Compound 18a) displays significant fluorescence enhancements in the presence of G4 structures (up to 300-fold), and good selectivity with respect to double-stranded DNA. 2-Di-1-ASP shows fluorimetric selectivity for parallel G4-DNA forms (c-kit2, c-myc, c-kit87up).
Cas No.
2156-29-8
分子式
C16H19IN2
分子量
366.24
储存和溶解度
DMSO:24 mg/mL (65.53 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years