4-Hydroxymephenytoin是抗癫痫药mephenytoin的代谢产物。Mephenytoin是CYP2C19的配体。
产品描述
4-Hydroxymephenytoin is the metabolism of an antiepileptic drug mephenytoin. Mephenytoin is used as a CYP2C19 substrate.
体外活性
4-Hydroxymephenytoin is a metabolism of mephenytoin, which is an antiepileptic drug, and used as a CYP2C19 substrate[1]. 4-Hydroxymephenytoin is used for developing UltraPerformance LC (UPLC) tandem mass spectrometry assays for evaluating CYP probe drugs and their relevant metabolites in human urine or plasma samples[2].
Cas No.
61837-65-8
分子式
C12H14N2O3
分子量
234.25
别名
(+/-)-4'-Hydroxymephenytoin
储存和溶解度
DMSO:90mg/mL (384.2mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years