3-UreIDOpropionic acid 是一种尿嘧啶代谢的中间产物。

Ureidopropionic acid is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase. It is further decomposed to beta-alanine via the enzyme beta-ureidopropionase. Ureidopropionic acid is essentially a urea derivative of beta-alanine. High levels of Ureidopropionic acid are found in individuals with beta-ureidopropionase (UP) deficiency. Enzyme deficiencies in pyrimidine metabolism are associated with a risk for severe toxicity against the antineoplastic agent 5-fluorouracil.

462-88-4

C4H8N2O3

132.119

Carbamoyl-b-alanine;3-酰脲丙酸;3-Ureidopropionic acid;Ureidopropionic acid

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years