QX77 是一种分子伴侣介导的自噬激活剂，可上调 LAMP2A 的表达。它可抑制 ES 细胞的自我更新，促进分化。它诱导 Rab11 上调，挽救 Rab11 下调和转运缺陷。

QX77 is a chaperone-mediated autophagy (CMA) activator.

Treatment with CMA activator QX77 rescues Rab11 down-regulation and trafficking deficiency in cystinotic cells. QX77 treatment also increases LAMP2A localization at the lysosomal membrane.

1798331-92-6

C16H13ClN2O2

300.74

QX77

DMSO:64 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years