Methacholine chloride 是副交感神经系统中的毒蕈碱-3 受体激动剂。它可用于测量气道高反应性，作为评估哮喘样症状和正常静息呼气流速的诊断辅助手段。它直接作用于平滑肌上的乙酰胆碱受体，引起收缩和气道狭窄。

Methacholine chloride is a quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma.

62-51-1

C8H18ClNO2

195.69

Acetyl-β-methylcholine chloride;醋甲胆碱;Mecholyl chloride;氯化乙酰甲胆碱;Methacholine Chloride

DMSO:42 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years