Bavisant 是一种特异性和口服活性的人 H3 受体拮抗剂。 Bavisant 可用于作用机制的研究，包括觉醒和认知以及 ADHD 的治疗。

Bavisant is a selective and orally active Human H3 receptor antagonist. Bavisant can be used in research on mechanisms of action, involving wakefulness and cognition and the treatment for ADHD.

Mean change from baseline in the total ADHD-RS-IV score at day 42 (primary efficacy endpoint) was -8.8 in the placebo group versus -9.3, -11.2, and -12.2 in the Bavisant 1 mg/day, 3 mg/day, and 10 mg/day groups, respectively; the change in the 10 mg/day group was not statistically superior to placebo, and hence statistical comparisons of the 1 mg/day and 3 mg/day groups with placebo based on a step-down closed testing procedure were not performed[1].

929622-08-2

C19H27N3O2

329.44

JNJ-31001074;Bavisant

DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years