Trimazosin 是一种具有口服活性的 quinazoline 衍生物，其结构与 prazosin 有关。Trimazosin 通过选择性阻断α1肾上腺素受体 (α1-adrenoceptors) 表现出降压 (hypotensive) 作用。

Trimazosin is an orally active, quinazoline derivative which is structurally related to prazosin. Trimazosin shows hypotensive effect by selectively block α1-adrenoceptors [1] [2].

Trimazosin (10–30 mg/kg; i.h.; once) produces graded decreases in blood pressure [3]. Animal Model: Conscious spontaneously hypertensive rats (SHR) [3] Dosage: 10–30 mg/kg Administration: Subcutaneous administration, once Result: Produced graded decreases in blood pressure.

35795-16-5

C20H29N5O6

435.47

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years