C24 dihydro 1-Deoxyceramide (m18:0/24:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 C24 dihydro 1-Deoxyceramide (m18:0/24:0) has been found in mouse embryonic fibroblasts (MEFs) following application of 1-deoxysphinganine alkyne or 1-deoxysphinganine-d3.3 It has also been found in mouse brain, spinal cord, and sciatic nerve at one, three, and six months of age.4

1645269-63-1

C42H85NO2

636.13

C24 dihydro 1-Deoxyceramide (m18:0/24:0);C24 dihydro 1-Deoxyceramide (m18:0/24:0)

Ethanol:30 mg/mL
DMF:20 mg/mL
DMSO:20 mg/mL
Ethanol:PBS (pH 7.2) (1:1):0.50 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years