Gallopamil 是一种苯烷基胺钙拮抗剂，以浓度依赖性方式抑制酸分泌 (IC50 = 10.9 μM)。Gallopamil 显示出抗心律失常和血管扩张剂的功效。

Gallopamil inhibits acid secretion in a concentration-dependent manner with an IC50 of 10.9 μM. Gallopamil is a potent antiarrhythmic and vasodilator agent. Gallopamil (Methoxyverapamil), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist.

Gallopamil(5 min) significantly reduces systolic and diastolic blood pressure measured without markedly influencing heart rate. Gallopamil (0.2 mg/kg;i.v.) markedly reduces ventricular tachycardia (VT) and totally prevents fibrillation (VF)[2].

16662-47-8

C28H40N2O5

484.63

Methoxyverapamil;戈洛帕米;Gallopamil

DMSO:100 mg/mL (206.34 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years