Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. 15-keto PGA1 is a metabolite of PGA1, produced by 15-hydroxy PG dehydrogenase. It can be produced from PGA1 in pig lung, trachea, aorta, and pulmonary artery tissue preparations. 15-keto PGA1, given at a concentration of 6 μM, causes vasoconstriction of rabbit lung that is comparable to that induced by angiotensin II.

61600-67-7

C20H30O4

334.45

15-keto Prostaglandin A1;15-keto Prostaglandin A1

DMF:50 mg/mL
Ethanol:50 mg/mL
DMSO:50 mg/mL
PBS (pH 7.2):1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years