MRS2395 是一种二戊酰衍生物，是一种有效的P2Y12受体拮抗剂。MRS2395 抑制 ADP 诱导的血小板活化，Ki为 3.6 μM。MRS2395 在 PGE1 存在下抑制大鼠血小板中 ADP 诱导的 cAMP，IC50为 7 μM。MRS2395 增强血小板致密颗粒释放以响应 TRAP-6。

MRS2395, an dipivaloyl derivative, is a potent P2Y12 receptor antagonist. MRS2395 inhibits ADP-induced platelet activation with a K i of 3.6 μM. MRS2395 inhibits cAMP induced by ADP in rat platelets in the presence of PGE1 with an IC 50 of 7 μM. MRS2395 enhances platelet dense granule release in response to TRAP-6 [1] [2].

491611-55-3

C20H30ClN5O4

439.94

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years