Lidoflazine is a high-affinity blocker of the HERG K+ channel and is an antianginal calcium channel blocker. It carries an obvious risk of QT interval prolongation and ventricular arrhythmia.

Lidoflazine inhibits effectively HERG current (IHERG). This recorded from HEK 293 cells stably expressing wild-type HERG (IC50: ~16 nM).

3416-26-0

C30H35F2N3O

491.62

Lidoflazine

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years