Anticancer agent 56 (compound 4d) 是一种具有类似药物特性的强效抗癌剂，对多种肿瘤细胞系具有抗癌活性 (IC50<3 μM)。Anticancer agent 56 诱导细胞周期阻滞在 G2/M 期，并触发线粒体凋亡通路。Anticancer agent 56 通过积累ROS，上调 BAX，下调BCL-2，激活Caspases 3, 7, 9起到抗癌作用。

Anticancer agent 56 (compound 4d) is a potent anti-cancer agent with drug-likeness properties, possessing anticancer activity against several cancer cell lines (IC 50<3 μM). Anticancer agent 56 induces cell cycle arrest at G2/M phase and triggers mitochondrial apoptosis pathway. Anticancer agent 56 acts by accumulation of ROS, up regulation of BAX, down regulation of Bcl-2 and activation of caspases 3, 7, 9 [1].

2241915-59-1

C20H18ClN3O3

383.83

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years