P-1075 是磺酰脲受体2相关的ATP敏感性的钾通道(SUR2-KIR6)的激活剂，EC50为 45 nM。它在兔子中通过打开线粒体 K (ATP) 通道产生活性氧，产生保护心脏的功效。

P-1075 is a potent sulfonylurea receptor 2-associated ATP-sensitive potassium channels (SUR2-KIR6) activator (EC50 = 45 nM). P-1075 opens opens mitoKATP channels and may be cardioprotective.

60559-98-0

C12H17N5

231.3

P-1075

DMSO:250 mg/mL (1080.85 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years