2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is an antimicrobial agent.1It is active against the Gram-negative bacteriaE. coli,P. aeruginosa, andS. marcescens(MICs = 64, 100, and 70 μg/ml, respectively), the Gram-positive bacteriaS. aureus,M. luteus, andB. cereus(MICs = 130, 100, and 50 μg/ml, respectively), and the fungiC. albicans,G. candidum,T. rubrum,F. oxysporum,A. flavus, andS. brevicaulis(MICs = 69-120 μg/ml). 2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is also a precursor in the synthesis of other antimicrobial agents, as well as compounds with anticancer activity.1,2

5351-71-3

C7H9N3S2

199.3

2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide

Ethanol:1 mg/mL
DMF:30 mg/mL
DMSO:PBS (pH 7.2) (1:4):0.20 mg/mL
DMSO:30 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years