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Dideoxyadenosine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dideoxyadenosine图片
CAS NO:4097-22-7
包装:10 mg
市场价:-1元

产品介绍
2',3'-Dideoxyadenosine 是HIV复制抑制剂,具有抗逆转录病毒活性和抗病毒的作用[1]。

产品描述

2',3'-Dideoxyadenosine is an inhibitor of HIV replication with antiretroviral activity and antiviral efficacy [1].

体外活性

2',3'-Dideoxyadenosine shows inhibition of HIV-1 and simian immunodeficiency virus (SIV) in MT-4 cells with EC 50 s of 5.27 and 5.3 μM, respectively. 2',3'-Dideoxyadenosine inhibits HIV-1 and HIV-2 in human T-lymphocyte CEM cells with EC 50 s of 4 μM and 8 μM, respectively. 2',3'-Dideoxyadenosine inhibits HIV-1 and HIV-2 in Molt 4/C8 cells with EC 50 s of 4 μM and 5.5 μM, respectively. 2',3'-Dideoxyadenosine inhibits HIV-1 and HIV-2 in C8166 cells with EC 50 s of 17 μM and 22 μM, respectively. 2',3'-Dideoxyadenosine inhibits murine sarcoma virus (MSV) in C3H/3T3 cells with an EC 50 of 24 μM [1].

Cas No.

4097-22-7

分子式

C10H13N5O2

分子量

235.24

别名

Dideoxyadenosine

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years