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p-cumylphenol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
p-cumylphenol图片
CAS NO:599-64-4
包装与价格:
包装价格(元)
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议

产品介绍
p-cumylphenol 可治疗新生大鼠肾小管囊肿形成。

产品描述

p-cumylphenol can treat R enal Tubular Cyst Formation in Newborn Rats.

体内活性

P-cumylphenol induced multiple renal cysts that developed in the collecting ducts of the outer medulla in neonatal rats, and it is suggested that epithelial cell proliferation may play some roles in the induction of cystic lesions.

动物实验

Fifteen animals per sex were treated orally with 300 mg/kg/day of p-cumylphenol for up to 18 days from postnatal day (PND) 4 and were sacrificed on PNDs 8, 12, 19 and 22 and after a 7 day recovery period. On PNDs 8 and 12, slight dilatation of the collecting ducts was frequently observed in the medulla and slight papillary necrosis was also noted in some cases. These dilated collecting ducts were lined with slightly hyperplastic epithelial cells. On PNDs 19 and 22, multiple large cystic changes arising from the collecting ducts in the outer medulla were seen.

Cas No.

599-64-4

分子式

C15H16O

分子量

212.292

别名

p-cumylphenol

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years