2-bromohexadecanoic acid 是一种不可代谢的棕榈酸酯类似物，可用作棕榈酰化抑制剂。它直接且不可逆地抑制所有 DHHC (Asp-His-His-Cys) 蛋白的棕榈酰转移酶活性。

2-bromohexadecanoic acid (2-BP, 2-bromopalmitate) is a non-metabolizable palmitate analogue, which can be used as palmitoylation inhibitor. 2-BP directly and irreversibly inhibits the palmitoyltransferase activity of all DHHC (Asp-His-His-Cys) proteins.

2-Bromohexadecanoic acid induces the interactions between GSDME-N and GSDME-C, and inhibits the GSDME-C palmitoylation, exhibiting chemotherapyinduced pyroptosis[1].

18263-25-7

C16H31BrO2

335.32

2-溴十六烷酸;2-BP;2-bromopalmitate;2-Bromohexadecanoic acid;2-Bromohexadecanoic acid

Methanol:100mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years