STING agonist 12b is an agonist of stimulator of interferon genes (STING).1It binds to STING (Kd= 26.4 μM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 μM, respectively). STING agonist 12b (40 μM) induces expression of TNF-a, IL-6, IP-10, and IL-1b in THP-1 cells.

2411100-70-2

C16H15NO2

253.301

STING Agonist 12b

DMSO:1 mg/mL
DMF:1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years