(S,R,S)-AHPC-PEG4-N3 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 (S,R,S)-AHPC 的 VHL 配体和 4 个单元 PEG linker。

(S,R,S)-AHPC-PEG4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology.

E3 ligase Ligand-Linker Conjugates 4 together with JQ1 triggers the intracellular destruction of BET proteins[1].

1797406-81-5

C32H47N7O8S

689.82

VHL Ligand-Linker Conjugates 5;E3 ligase Ligand-Linker Conjugates 4;VH032-PEG4-N3;(S,R,S)-AHPC-PEG4-N3

DMSO:50 mg/mL (72.48 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years