HA-100 hydrochloride is a potent protein kinase inhibitor, with IC 50 s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase ( PKG ), cAMP-dependent protein kinase ( PKA ), protein kinase C ( PKC ) and MLC-kinase , respectively. HA-100 hydrochloride also used as a ROCK inhibitor.

HA-100 hydrochloride inhibits MLC-kinase and PKC competitively with respect to ATP, with K i s of 61 and 6.5 μM, respectively[1].

141543-63-7

C13H16ClN3O2S

313.8

HA-100 hydrochloride

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years