FLT3/ITD-IN-3 (Compound 19) 是一种有效的FLT3-ITD抑制剂，对FLT3D835Y、FLT3和 FLT3-ITD 的IC50值分别为 0.3、0.4 和 0.9 nM。FLT3/ITD-IN-3 有效抑制 FLT3 的磷酸化，对急性髓系白血病细胞具有良好的抗增殖活性。

FLT3/ITD-IN-3 (Compound 19) is a potent FLT3 internal tandem duplications ( FLT3-ITD ) inhibitor with IC 50 values of 0.3, 0.4 and 0.9 nM against FLT3 D835Y, FLT3 and FLT3-ITD, respectively. FLT3/ITD-IN-3 potently inhibits the phosphorylation of FLT3 and displays excellent antiproliferative activities against acute myeloid leukemia cell lines [1].

2489446-47-9

C22H26ClN7O2

455.94

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years