JAK 3 inhibitor IV 是一种 JAK1/3 抑制剂，pIC50 为 4.4/7.1，对 JAK2 几乎没有活性，对 EGFR 有适度的作用；还发现对转谷氨酰胺酶敏感。

JAK 3 inhibitor IV is a JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.

58753-54-1

C16H19NO

241.334

ZM 39923 hydrochloride;Jak3 inhibitor IV;JAK 3 inhibitor IV

DMSO:36.8 mg/mL(100 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years