LDHA/PDKs-IN-1 (compound 20e) 是一种有效的 PDKs 和 LDHA 双重抑制剂，IC50s 分别为 0.8 和 0.15 μM。LDHA/PDKs-IN-1 减少 A549 细胞增殖，EC50为 13.2 μM，减少乳酸形成，增加耗氧量。LDHA/PDKs-IN-1 具有研究癌症疾病的潜力。

LDHA/PDKs-IN-1 (compound 20e) is a potent and dual inhibitor of PDKs and LDHA with IC 50 s of 0.8 and 0.15 μM, respectively. LDHA/PDKs-IN-1 reduces A549 cell proliferation with an EC 50 of 13.2 μM and decreases the lactate formation, and increases oxygen consumption. LDHA/PDKs-IN-1 has the potential for the research of cancer diseases [1].

2490699-40-4

C19H21FN2O4

360.38

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years