Necroptosis-IN-3(Compound 69) 是一种坏死性凋亡 (necroptosis) 抑制剂，抑制 TNF-α 诱导的坏死性凋亡。Necroptosis-IN-3(Compound 69) 也抑制 11β-HSD1。

Necroptosis-IN-3 (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis. Necroptosis-IN-3 (Compound STX1638) also inhibits 11β-HSD1.

TNF-α-IN-8 (Compound 69) (0.030-100 μ M; 24 h) inhibits TNF-α induced necrosis of human Jurkat T cells with FADD deficiency [1].

547698-18-0

C12H17NOS

223.33

Cyclohexanecarboxamide, N-(2-thienylmethyl)-;Necroptosis-IN-3

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years