3'-HydroxypteROStilbene是天然紫檀芪类似物，通过诱导细胞凋亡和自噬，有效抑制人结肠癌细胞的生长。它抑制 PI3K/Akt/mTOR/p70S6K 和 p38MAPK 途径并激活 ERK1/2，JNK1/2 MAPK途径。

3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells with IC50s of 9.0, 40.2, and 70.9 μM for COLO 205, HCT-116, and HT-29 cells, respectively, by inducing apoptosis and autophagy. 3'-Hydroxypterostilbene inhibits the p38MAPK , and PI3K/Akt/mTOR/p70S6K pathways and activates the ERK1/2, JNK1/2 MAPK pathways[1].

475231-21-1

C16H16O4

272.3

3’-羟基紫檀茋;3'-羟基紫檀茋;3'-HPT;3'-Hydroxypterostilbene

DMSO:26 mg/mL (954.83 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years