Solifenacin Succinate 是毒蕈碱受体拮抗剂，对M1、M2和M3受体的pKi值分别为 7.6、6.9 和 8.0。

Solifenacin succinate is a quinuclidine and tetrahydroisoquinoline derivative and selective M3 MUSCARINIC ANTAGONIST. It is used as a UROLOGIC AGENT in the treatment of URINARY INCONTINENCE.

Solifenacin succinate是一种新型毒蕈碱受体拮抗剂,用于治疗膀胱过度活动症。Solifenacin与奥昔布宁联用,在豚鼠上分离出的膀胱平滑肌细胞和小鼠上分离出的颌下腺细胞中,可以抑制毒蕈碱受体M3介导的细胞内钙离子的调动。

242478-38-2

C23H26N2O2·C4H6O4

480.56

YM905;索非那新琥珀酸盐;Solifenacin succinate

DMSO:10mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years