ZDWX-25 是一种高效的GSK-3β和DYRK1A双重抑制剂，对 GSK-3β 的IC50为 71 nM。ZDWX-25 对 SH-SY5Y 和 HL-7702 细胞具有显著的细胞毒性。ZDWX-25 可用于阿尔兹海默症的研究。

ZDWX-25 is a highly potent GSK-3β and DYRK1A dual inhibitor with an IC 50 value of 71 nM for GSK-3β. ZDWX-25 possesses significant cytotoxic activities against SH-SY5Y and HL-7702 cells. ZDWX-25 can be used for researching alzheimer's disease [1].

2668297-70-7

C17H15N3O3

309.32

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years