Mefloquine 是一种喹啉抗疟药，是一种抗 SARS-CoV-2 进入抑制剂。 Mefloquine 也是一种 K+ 通道 (KvQT1/minK) 拮抗剂，IC50 为 ~1 μM。它可用于疟疾、系统性红斑狼疮和癌症研究。

Mefloquine, a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic lupus erythematosus, and cancer research.

53230-10-7

C17H16F6N2O

378.31

Ro-215998;氟甲喹羟哌啶;Lariam;Ro 215998;Ro215998;WR 142490;Mefloquine

DMSO:55 mg/ml (145.38 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years