Mt KARI-IN-5 (compound 6c) 是一种有效的结核分歧杆菌酮醇酸还原异构酶 I (MtbKARI)抑制剂,Ki为 4.72 μM。Mt KARI-IN-5 对MtbH37Rv 具有抑制活性 (MIC = 1.56 μM),且具有较低的细胞毒性 (HEK IC50>64 μg/mL)。
产品描述
Mt KARI-IN-5 (compound 6c) is a potent Mycobacterium tuberculosis ketol-acid reductoisomerase ( Mtb KARI) inhibitor with a K i value of 4.72 μM. Mt KARI-IN-5 has inhibitory activity against Mtb H37Rv (MIC = 1.56 μM) and low cytotoxicity (HEK IC 50 >64 μg/mL) [1]
Cas No.
2413974-69-1
分子式
C14H10N4O5S3
分子量
410.45
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years