GR 125743 是选择性的5-HT1B/1D受体拮抗剂，与野生型的人 h5-HT1B和 5-HT1D结合的pKi分别为 8.85 和 8.31，可用于帕金森病和心血管疾病的研究。
产品描述
GR 125743 is a novel antagonist of 5-HT1B/1D receptor.
体外活性
GR-125743, a new radiolabelled derivative of a compound that exhibits selective antagonistic properties with respect to the serotonin human (h5-HT1D) and human (h5-HT1B) receptors.?The compound has been characterized for its ability to label the cloned h5-HT1D and h5-HT1B receptors.
Cas No.
148547-33-5
分子式
C25H28N4O2
分子量
416.525
别名
GR 125743
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
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