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NAAA-IN-3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1831115-59-3
包装与价格:
包装价格(元)
5 mg电议
50 mg电议
100 mg电议

产品介绍
NAAA-IN-3 (Compound 17a) 是一种有效的、选择性的NAAA抑制剂,IC50为 50 nM。NAAA 是一种半胱氨酸酰胺酶,它优先水解内源性生物脂棕榈酰乙醇酰胺 (PEA) 和油酰乙醇酰胺 (OEA)。PEA 是核过氧化物酶体增殖物激活受体-α (PPAR-α) 的内源性激动剂,PPAR-α 是炎症和疼痛的关键调节因子。 NAAA-IN-3 的潜在作用是作为炎症和疼痛的治疗剂。

产品描述

NAAA-IN-3 (Compound 17a) is a potent and selective NAAA inhibitor with an IC50 of 50 nM. NAAA is a cysteine amidase which preferentially hydrolyzes the endogenous biolipids palmitoylethanolamide (PEA) and oleoylethanolamide (OEA). PEA is an endogenous agonist of the nuclear peroxisome proliferator-activated receptor-α (PPAR-α), which is a key regulator of inflammation and pain. The potential role of NAAA-IN-3 is as a therapeutic agent for the treatment of inflammation and pain.

Cas No.

1831115-59-3

分子式

C17H16N2O

分子量

264.32

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years