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(R)-(+)-Linoleyl-1'-Hydroxy-2'-Propylamide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(R)-(+)-Linoleyl-1'-Hydroxy-2'-Propylamide图片
CAS NO:220556-74-1
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议

产品介绍

产品描述

N-Acyl ethanolamines have diverse biological actions that are strongly affected by the associated acyl group. Linoleoyl ethanolamide (LOEA) has potential signaling roles in aging and neurological functioning. LOEA has a weak affinity for cannabinoid (CB) receptors (Ki = 10, 25 μM for CB1, CB2, respectively). Although hydrolized by fatty acid amide hydrolase (FAAH; Ki = 9 μM) it also inhibits FAAH and inhibits voltage-gated K+ channels. (R)-(+)-Linoleyl-1'-hydroxy-2'-propylamide is a homolog of LOEA, characterized by the addition of an (R)-α-methyl group at the methylene carbon adjacent to the amide nitrogen. A similar modification of arachidonoyl ethanolamide to produce R-1 methanandamide imparts higher affinity for the CB receptor as well as improved metabolic stability. The physiological actions of this compound have not been evaluated.

Cas No.

220556-74-1

分子式

C21H39NO2

分子量

337.54

别名

(R)-(+)-Linoleyl-1'-Hydroxy-2'-Propylamide

储存和溶解度

Ethanol:20 mg/mL
DMF:11 mg/mL
DMSO:5 mg/mL
Ethanol:PBS (pH 7.2)(1:2):11 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years