L-DABA 是GABA转氨酶的弱抑制剂，IC50值大于500 μM，具有抗肿瘤活性。

L-DAB HBR is an inhibitor of GABA transaminase (IC50 >500 μM).

L-2,4-Diaminobutyric acid(DABA) was a non-linear, non-competitive inhibitor of GABA transaminase activity. The DABA-induced elevation of GABA levels paralleled the inhibition of GABA transaminase activity. DABA was a more effective inhibitor of GABA transaminase in vivo than in vitro, and this inhibition probably produced the elevation of GABA levels. The neurotoxicity of DABA appears to produce a use in GABA replacement therapy[1].

1758-80-1

C4H10N2O2

118.136

L-2,4-二氨基丁酸氢溴酸盐;L-DAB HBR;L-2,4-Diaminobutyric acid;L-DABA

H2O:Insoluble
DMSO:Insoluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years