PACAP-38 (31-38), human, mouse, rat acetate 是 PAC1 受体的激活剂。PACAP-38 (31-38), human, mouse, rat acetate 对交感神经元 NPY 和儿茶酚胺的产生具有强效、有效和持续的刺激作用，可用于神经营养和神经保护研究。

PACAP-38 (31-38), human, mouse, rat acetate is an activator of PAC1 receptor. PACAP-38 (31-38), human, mouse, rat acetate demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production and can

PACAP-38 (31-38), human, mouse, rat acetate (0.01-10 nM; HEK 293 cells) stimulates neural cells to express endogenous PAC1 receptors by cAMP accumulation and by an increase in cytosolic free calcium and induces elevation of the intracellular Ca2+ concentration in a dose-dependent manner with an EC50 value of 0.81 nM. PACAP-38 (31-38), human, mouse, rat acetate (300 nM; 4 h) stimulates the generation of APPsα in neural cells[1]. PACAP-38 (31-38), human, mouse, rat acetate (0.01 nM; 48 h) elicits potent and efficacious stimulation of NPY secretion from SCG neuronal cultures[2]. PACAP-38 (31-38), human, mouse, rat acetate (100 nM; 14 d) produces sustained stimulated NPY and catecholamine secretionmpathetic neurons[2]. PACAP-38 (31-38), human, mouse, rat acetate (100 nM; 2 min; NCI-H838 cells) induces EGFR, HER2, and ERK tyrosine phosphorylation. PACAP-38 (31-38), human, mouse, rat acetate (10 nM; 48 h) stimulates the growth of NCI-H838 cells. PACAP-38 (31-38), human, mouse, rat acetate (100 nM; 30 min; NCI-H838 cells) induces EGFR tyrosine phosphorylation with generates ROS and increases ROS levels by 51%[3].

TP1618L

C49H87N17O13

1122.32

PACAP-38 (31-38), human, mouse, rat acetate(138764-85-9 Free base);PACAP-38 (31-38), human, mouse, rat acetate

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years