Potent neuropeptide Y (NPY) Y5 receptor agonist (pEC50 values are 7.82, 6.28, 6.44 and >6 at rat Y5, Y4, Y1 and Y2 receptors respectively) that displays >26-fold, >1000-fold and >1000-fold selectivity over Y1, Y2 and Y4 receptors respectively. Induces hyperphagia, body weight gain, adiposity, hypercholesterolemia, hyperinsulinemia and hyperleptinemia in vivo. Orally active.

153549-84-9

C196H289N55O56

4311.77

[D-Trp34]-Neuropeptide Y

20% acetonitrile:0.20 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years