产品描述
2-oxo Clopidogrel is an intermediary metabolite of clopidogrel . Clopidogrel is a prodrug that is converted to its active metabolite via two sequential oxidative steps. The first step leads to formation of 2-oxo clopidogrel, followed by conversion to the active metabolite, which binds specifically and irreversibly to the platelet P2Y12 purinergic receptor, inhibiting ADP-mediated platelet activation and aggregation.
Cas No.
109904-27-0
分子式
C16H16ClNO3S
分子量
337.82
别名
2-oxo Clopidogrel
储存和溶解度
DMF:PBS (pH 7.2) (1:20):0.04 mg/mL
DMSO:20 mg/mL
Ethanol:5 mg/mL
DMF:25 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years