产品描述
Calmodulin antagonist-1 (W-7) is a calmodulin (CaM) antagonist. Calmodulin antagonist-1 inhibits calmodulin-activated Ca 2+ -phosphodiesterase (PDE) (IC 50 =28 μM). Calmodulin antagonist-1 also inhibits trypsin-treated Ca 2+ -PDE (IC 50 =375 μM) in a competitive fashion with respect to cyclic GMP and the K i value is 300 μM.
Cas No.
78957-84-3
分子式
C14H18Cl2N2O2S
分子量
349.28
别名
Calmodulin antagonist-1
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years