11-Aminoundecanoic acid 是一种属于 alkyl chain 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
11-Aminoundecanoic acid is an alkyl chain based PROTAC linker can be used in PROTAC synthesis.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
2432-99-7
分子式
C11H23NO2
分子量
201.31
别名
11-Aminoundecanoic acid
储存和溶解度
DMSO:3.22 mg/mL (16 mM),ultrasonic and adjust pH to 2 with HCl)
H2O:< 0.1 mg/mL (insoluble)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years