1,3-Dibromo-5,5-dimethylhydantoin 是一种属于 alkyl chain 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
1,3-Dibromo-5,5-dimethylhydantoin is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
77-48-5
分子式
C5H6Br2N2O2
分子量
285.92
别名
1,3-Dibromo-5,5-dimethylhydantoin
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years