Succinic acid sodium 是一种口服有效的抗焦虑剂。Succinic acid sodium 对体内的结肠上皮细胞增殖有抑制作用。Succinic acid sodium 可下调KCNMB1(钾通道亚基 β1) 和TET1(10-11 易位 1) 的表达。Succinic acid sodium 可用于妊娠期高血压的研究。
产品描述
Succinic acid sodium is a potent and orally active anxiolytic agent. Succinic acid sodium shows inhibitory effects on colonic epithelial cell proliferation in vivo. Succinic acid sodium can down-regulate the expression of KCNMB1 (potassium channel subunit β1) and TET1 (ten eleven translocation 1). Succinic acid sodium can be used for gestational hypertension research [1] [2] [3].
体内活性
Succinic acid sodium (3.0 or 6.0 mg/kg, PO) increased the percentage of entries into open arms and of time spent on open arms [1]. succinic acid (3.0, 6.0, and 12.0 mg/kg, IP) caused significant increases in food intake during 5 min when compared with the vehicle [1]. Succinic acid sodium (100 mM) infused into rat colons significantly inhibits colonic cell proliferation and reduced crypt size [2].
Cas No.
14047-56-4
分子式
C4H6O4.xNa
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years