D-threo-PPMP is a glucosylceramide (GlyCer) synthetase inhibitor.1,2It is the active enanantiomer and enzymatic inhibitory component of the racemic DL-threo-PPMP . In MDCK kidney epithelial cells, D-threo-PPMP induces a 70% reduction in cell growthin vitroat 20 μM and significantly inhibits DNA synthesis at 3 μM.3

139889-65-9

C29H51ClN2O3

511.18

D-threo-PPMP hydrochloride

Ethanol:Soluble
Methanol:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years