Dimethomorph 是一种吗啉类杀菌剂，属于甾醇生物合成抑制剂类杀菌剂，可抑制真菌细胞壁的形成。Dimethomorph 抑制了oomycete fungi，P. citrophthora，P. parasitica，P. capsici，和P. infestans的菌丝生长 (EC50=0.14 μg/mL，0.38 μg/mL，<0.1 μg/mL 和 0.16-0.3 μg/mL)，但是对绿藻物种C. vulgaris和S. obliquus的活性较低 (EC50=47.46 μg/mL 和 44.87 μg/mL)。在 MDA-kb2 人乳腺癌细胞的报告基因分析中，Dimethomorph 抑制雄激素受体 (AR) 的活性，而在酵母抗雄激素筛选中不起作用 (IC20=0.263 μM 和 38.5 μM)。

Dimethomorph is a morpholine fungicide belonging to the fungicide group of sterol biosynthesis inhibitors that inhibits fungal cell wall formation. Dimethomorph inhibits mycelial growth of the oomycete fungi, P. citrophthora, P. parasitica, P. capsici, and P. infestans ( EC 50 s=0.1, 0.38,<0.1, and 0.16-0.3 μg/mL, respectively), but is less active against the green algae species C. vulgaris or S. obliquus in vitro (EC 50 s=47.46 and 44.87 μg/mL, respectively). Dimethomorph inhibits androgen receptor (AR) activity in a reporter assay in MDA-kb2 human breast cancer cells but not in a yeast antiandrogen screen ( IC 20 s=0.263 and 38.5 μM, respectively).

110488-70-5

C21H22ClNO4

387.86

Dimethomorph

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years